corosolic acid, also known as 2α-hydroxy acid, is present in Lagerstroemia speciosa (commonly known as Barnabas, abound in the Philippines Islands), loquat and other plants in a triterpenoids.
In vivo results show that corosolic acid through glucose transporter excited to promote cell uptake and utilization of glucose in order to achieve the hypoglycemic effect. Koroso acid on the glucose transporter of the excitatory effect similar to insulin, therefore, Koroso acid, also known as "plant insulin." Animal experiments showed that Koroso acid in normal rats and hereditary diabetic mice showed a significant hypoglycemic effect. Koroso acid are weight loss, clinical study found that after taking the drug to regulate insulin and blood sugar levels, the trend has obvious weight loss (average weight loss on 0.908-1.816Kg), the process is slow and without dieting. Koroso acid also has many other biological activities, such as TPA-induced inflammation significantly inhibit the anti-inflammatory effects are the strongest commercially available anti-inflammatory drug indomethacin; It also has DNA polymerase inhibitory activity as well as inhibit the growth of various tumor cells. In recent years, also found that anti-virus and anti-cardiovascular disease effect. Currently, the natural products as nutritional supplements in the United States has listed the same time, the treatment of diabetes Phase III clinical trial, recently through the FDA. The effect of the treatment of diabetes with insulin than with oral effects of significant toxicity, and easy use, and effect of insulin considerable. Koroso acid as obesity and type 2 diabetes prevention and control of plant drugs and functional materials of natural health food and medicine, has become a hot market, products, product demand.
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